Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 14/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619343 | 0.88 | GRIA2 (0.52) | GRIA2PTGS1 | |
| SCHEMBL5621573 | 0.84 | GRIA2 (0.43) | GRIA2 | |
| SCHEMBL5619273 | 0.81 | NPC1 (0.46) | GRIA2KMT2A | |
| SCHEMBL5620763 | 0.81 | GRIA2 (0.52) | GRIA2 | |
| SCHEMBL5620626 | 0.80 | PARP10 (0.47) | GRIA2 | |
| SCHEMBL5620058 | 0.78 | GRIA2 (0.41) | GRIA2MEN1KMT2A | |
| SCHEMBL5621041 | 0.78 | GRIA2 (0.40) | GRIA2 | |
| SCHEMBL5620019 | 0.75 | GRIA2 (0.39) | GRIA2PTGS1CYP2D6 | |
| SCHEMBL5620642 | 0.73 | GRIA2 (0.73) | GRIA2 | |
| SCHEMBL5620490 | 0.71 | GRIA2 (0.71) | GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253161-B2 | Benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2007-08-07 | — | — | US | disclosed |
| US-20050124606-A1 | Novel benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124606-A1 | Novel benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | NR4A3, NR5A2, NR4A1 | GRIA2 537/4885PTGS1 2935/4885MEN1 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.