Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.57 |
| ▸ | F10 | P00742 | 7/20 | 0.51 |
| ▸ | FPR1 | P21462 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620892 | 0.89 | FPR2 (0.57) | FPR2F10FPR1HPGD | |
| SCHEMBL5619981 | 0.86 | FPR2 (0.53) | FPR2F10FPR1HPGD | |
| SCHEMBL4485882 | 0.77 | FPR2 (0.69) | FPR2F10FPR1 | |
| SCHEMBL22179684 | 0.76 | FPR2 (0.80) | FPR2FPR1 | |
| SCHEMBL23142150 | 0.76 | FPR2 (0.80) | FPR2FPR1 | |
| SCHEMBL4490944 | 0.75 | F10 (0.54) | FPR2F10FPR1HPGD | |
| SCHEMBL5620894 | 0.75 | FPR2 (0.53) | FPR2F10FPR1HPGD | |
| SCHEMBL4464011 | 0.74 | FPR2 (0.53) | FPR2F10FPR1HPGD | |
| SCHEMBL4464013 | 0.73 | F10 (0.54) | FPR2F10FPR1 | |
| SCHEMBL4475463 | 0.73 | F10 (0.54) | FPR2F10FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157470-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-02 | — | — | US | claimed |