Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 14/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482948 | 0.90 | BRAF (0.47) | BRAF | |
| SCHEMBL5776694 | 0.84 | BRAF (0.47) | BRAF | |
| SCHEMBL4483034 | 0.82 | BRAF (0.49) | BRAF | |
| SCHEMBL4478013 | 0.80 | BRAF (0.40) | GPR142BRAF | |
| SCHEMBL4490549 | 0.80 | BRAF (0.52) | BRAF | |
| SCHEMBL4495840 | 0.80 | BRAF (0.49) | BRAF | |
| SCHEMBL4487287 | 0.79 | BRAF (0.48) | BRAF | |
| SCHEMBL4465326 | 0.78 | P4HTM (0.41) | BRAF | |
| SCHEMBL4499185 | 0.78 | BRAF (0.48) | BRAF | |
| SCHEMBL6194179 | 0.77 | BRAF (0.49) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166628-B2 | Cytokine inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | claimed |