Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 16/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482948 | 0.94 | BRAF (0.47) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4483034 | 0.94 | BRAF (0.49) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4495780 | 0.91 | BRAF (0.52) | BRAFMAPK14 | |
| SCHEMBL4495840 | 0.90 | BRAF (0.49) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4487287 | 0.89 | BRAF (0.48) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4499185 | 0.88 | BRAF (0.48) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL6194179 | 0.88 | BRAF (0.49) | BRAFMAPK14 | |
| SCHEMBL4490549 | 0.88 | BRAF (0.52) | BRAFMAPK14 | |
| SCHEMBL4483178 | 0.87 | BRAF (0.49) | BRAFMAPK14 | |
| Pivalamide SCHEMBL6807091 | 0.87 | BRAF (0.49) | BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567507-B1 | 1,2,3- TRIAZOLE AMIDE DERIVATIVES AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2006-06-14 | — | — | EP | claimed |