SCHEMBL562069

SCHEMBL562069

CC(CON(Cc1ccccc1)Cc1ccccc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7086877 0.90 CYP1A2 (0.42) HPGDKMT2AMEN1CA12CA9
SCHEMBL10352071 0.86 KMT2A (0.46) HPGDKMT2AMEN1CA12CA9
SCHEMBL2238584 0.81 CYP1A2 (0.49) KMT2AMEN1CA12CA9LMNA
SCHEMBL8390332 0.76 KMT2A (0.49) HPGDKMT2AMEN1CA12CA9
SCHEMBL561237 0.74 CSNK1E (0.44)
SCHEMBL800946 0.74 SLC1A1 (0.55) KMT2AMEN1CA9ALDH1A1TSHR
SCHEMBL3034357 0.74 SLC1A1 (0.55) KMT2AMEN1CA9ALDH1A1TSHR
SCHEMBL7494382 0.74 SLC1A1 (0.55) KMT2AMEN1CA9ALDH1A1TSHR
SCHEMBL562608 0.73 HPGD (0.47) HPGDKMT2AMEN1CA12CA9
SCHEMBL19209334 0.71 HPGD (0.49) HPGDKMT2AMEN1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240462-B1 SUBSTITUTED AMINOOXYPROPANOATE CIBA-GEIGY AG (CH) 1990-08-01 EP claimed
EP-0240462-A2 Substituted aminooxypropanoate CIBA-GEIGY AG (CH) 1987-10-07 EP claimed
EP-2880092-B1 PHOSPHITE COMPOSITIONS SI GROUP SWITZERLAND CHAA GMBH (CH) 2020-09-30 EP disclosed
EP-2459576-B1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER ADDIVANT SWITZERLAND GMBH (CH) 2018-11-21 EP disclosed
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP disclosed
EP-2917276-B1 STABILIZED HIGH-DENSITY POLYETHYLENE COMPOSITION WITH IMPROVED RESISTANCE TO DETERIORATION AND STABILZER SYSTEM EQUISTAR CHEM LP (US) 2018-07-18 EP disclosed
EP-2459574-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2018-06-20 EP disclosed
EP-1885787-B1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM CO (US) 2018-01-10 EP disclosed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP disclosed
EP-2917276-A1 STABILIZED HIGH-DENSITY POLYETHYLENE COMPOSITION WITH IMPROVED RESISTANCE TO DETERIORATION AND STABILZER SYSTEM Equistar Chemicals LP (US) 2015-09-16 EP disclosed
EP-2459578-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2015-08-19 EP disclosed
US-5141975-A Melt processability, discoloration inhibition GENERAL ELECTRIC COMPANY (US) 1992-08-25 US disclosed
US-5137950-A Reacting phosphorous trichloride with alcohol; polymer stabilizer BORG-WARNER SPECIALTY CHEMICALS, INC. (US) 1992-08-11 US disclosed
US-5124472-A From tetrahydroabiethyl alcohol GENERAL ELECTRIC COMPANY (US) 1992-06-23 US disclosed
EP-0460461-A1 Hydrolytically stable phosphites GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5023285-A Melt flow and color stabilizers for polymers G E SPECIALTY CHEMICALS (US) 1991-06-11 US disclosed
EP-0240462-B1 SUBSTITUTED AMINOOXYPROPANOATE CIBA-GEIGY AG (CH) 1990-08-01 EP disclosed
EP-0356687-A1 Bis (tri-tertiary-alkylphenoxy) diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
EP-0356688-A2 3, 9-diphosphaspiroundecanes and process for making 3, 9-diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
EP-0240462-A2 Substituted aminooxypropanoate CIBA-GEIGY AG (CH) 1987-10-07 EP disclosed