Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620465 | 0.86 | GRIA2 (0.54) | GRIA2FFAR1FFAR4AOC3 | |
| SCHEMBL13488121 | 0.80 | CA1 (0.45) | GRIA2ALDH1A1AOC3 | |
| SCHEMBL5619678 | 0.72 | GRIA2 (0.73) | GRIA2ALDH1A1 | |
| SCHEMBL2152720 | 0.71 | GRIA2 (1.00) | GRIA2 | |
| SCHEMBL21266522 | 0.70 | CA1 (0.49) | GRIA2ALDH1A1AOC3 | |
| SCHEMBL30485944 | 0.70 | CA1 (0.49) | GRIA2ALDH1A1AOC3 | |
| SCHEMBL5185098 | 0.70 | KMT2A (0.48) | ALDH1A1TDP1L3MBTL1AOC3 | |
| SCHEMBL11961604 | 0.69 | ALDH1A1 (0.54) | GRIA2ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL14159539 | 0.69 | ALDH1A1 (0.80) | ALDH1A1HTTTDP1L3MBTL1LYN | |
| SCHEMBL10013917 | 0.69 | ALDH1A1 (0.80) | ALDH1A1HTTTDP1L3MBTL1LYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253161-B2 | Benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2007-08-07 | — | — | US | disclosed |
| CN-1289509-C | Benzothiazine and benzothiadiazine derivatives, method for preparing same and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2006-12-13 | — | — | CN | disclosed |
| US-20050124606-A1 | Novel benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-06-09 | — | — | US | disclosed |
| CN-1606560-A | Benzothiazine and benzothiadiazine derivatives, method for preparing same and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2005-04-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124606-A1 | Novel benzothiazine and benzothiadiazine derivatives method for preparing same and pharmaceutical compositions containing same | NR4A3, NR5A2, NR4A1 | GRIA2 537/4885ALDH1A1 2161/4885HTT 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.