SCHEMBL56215

SCHEMBL56215

C1=COC(Cc2ccccc2)O1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.41
CALM1 P0DP23 1/20 0.39
GBA1 P04062 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAOB P27338 1/20 0.38
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CTRB1 P17538 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6432088 0.79 SLC6A2 (0.44) TAAR1CALM1GBA1SLC6A2SLC6A4
SCHEMBL2246577 0.76 TAAR1 (0.50) TAAR1TDP1SLC6A2SLC6A4SLC6A3
SCHEMBL15710064 0.74 TAAR1 (0.46) TAAR1MAOB
SCHEMBL22722 0.73 GBA1 (0.42) TAAR1GBA1LTB4RLTB4R2SLC6A2
SCHEMBL5269537 0.73 GBA1 (0.42) TAAR1GBA1SLC6A2SLC6A4SLC6A3
SCHEMBL3617768 0.73 MAOB (0.44) MAOBLTB4RLTB4R2CTRB1
SCHEMBL30754361 0.72 LTB4R (0.44) TAAR1GBA1MAOBLTB4RLTB4R2
SCHEMBL1558896 0.72 LTB4R (0.44) TAAR1GBA1MAOBLTB4RLTB4R2
SCHEMBL1100674 0.72 GBA1 (0.37) TAAR1GBA1SLC6A2SLC6A4SLC6A3
SCHEMBL30754350 0.72 LTB4R (0.44) TAAR1GBA1MAOBLTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10649 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025227116-A1 EPH-EPHRIN TETRAMERIZATION INHIBITORS THAT TARGET A PREVIOUSLY UNKNOWN AND VERY HIGH-AFFINITY CHELATOR-TYPE INTERMOLECULAR PROTEIN-PROTEIN INTERACTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-30 WO claimed
EP-4570313-A2 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP claimed
US-11839613-B2 Pyrimidine derivatives as PGE2 receptor modulators IDORSIA PHARMACEUTICALS LTD (CH) 2023-12-12 US claimed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP claimed
US-20230014962-A1 Quinoline compound and use thereof SKYRUN PHARMA CO LTD (CN) 2023-01-19 US claimed
EP-3658141-B1 TREATING PATHOLOGICAL CONDITIONS BY DIRECT AND INDIRECT TARGETING OF SIRPALPHA - CD47 INTERACTION STICHTING HET NEDERLANDS KANKER INST ANTONI VAN LEEUWENHOEK ZIEKENHUIS (NL) 2022-11-16 EP claimed
EP-4083031-A1 QUINOLINE COMPOUND AND APPLICATION THEREOF Skyrun Pharma Co., Ltd. (CN) 2022-11-02 EP claimed
US-20220280527-A1 TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT PURDUE PHARMA L.P. (US) 2022-09-08 US claimed
US-20210379052-A1 QUINOLINE DERIVATIVE HAVING INDOLEAMINE-2,3-DIOXYGENASE INHIBITORY ACTIVITY SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2021-12-09 US claimed
EP-3625223-B1 PYRIMIDINE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2021-08-11 EP claimed
WO-2000042019-A1 6-ARYLPHENANTHRIDINES WITH PDE-IV INHIBITING ACTIVITY BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-07-20 WO claimed
US-6090797-A ADJUSTMENT OF GLUCOSE METABOLISM; HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS NOVO NORDISK A/S (DK) 2000-07-18 US claimed
WO-2000038687-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-07-06 WO claimed
EP-1000619-A2 Method for treating glaucoma Pfizer Products Inc. (US) 2000-05-17 EP claimed
EP-0946501-A1 PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS PFIZER INC. (US) 1999-10-06 EP claimed
WO-1998028264-A1 PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS PFIZER INC. (US) 1998-07-02 WO claimed
EP-0537517-B1 Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates BAYER AG (DE) 1997-01-22 EP claimed
EP-0537518-B1 Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use BAYER AG (DE) 1996-04-17 EP claimed
US-5420308-A 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products BAYER AKTIENGESELLSCHAFT (DE) 1995-05-30 US claimed
EP-0537518-A1 Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use BAYER AG (DE) 1993-04-21 EP claimed