Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18614370 | 0.99 | PARP1 (0.98) | PARP1PARP2 | |
| SCHEMBL1298103 | 0.89 | PARP1 (0.80) | PARP1PARP2 | |
| SCHEMBL630129 | 0.85 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL7702651 | 0.84 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL630259 | 0.84 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL633643 | 0.84 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL630441 | 0.83 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL630980 | 0.83 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL631516 | 0.83 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL6872050 | 0.82 | PARP1 (0.70) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39608-E1 | Substituted benzimidazoles and their use as PARP inhibitors | ABBOTT GMBH & CO. KG (DE) | 2007-05-01 | — | — | US | disclosed |
| US-6448271-B1 | SUCH AS 2-(PIPERIDIN-4-YL)BENZIMIDAZOLE-4-CARBOXAMIDE; INHIBITORS OF ENZYME POLY(ADP-RIBOSE)POLYMERASE; IMPROVED WATER SOLUBILITY | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |