⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26726102 | 0.87 | — | — | |
| SCHEMBL17517790 | 0.85 | — | — | |
| SCHEMBL2176546 | 0.80 | PRKCA (0.32) | — | |
| SCHEMBL2176554 | 0.80 | PRKCA (0.32) | — | |
| SCHEMBL16031858 | 0.80 | — | — | |
| SCHEMBL9685316 | 0.80 | — | — | |
| SCHEMBL2849077 | 0.79 | — | — | |
| SCHEMBL4196095 | 0.79 | — | — | |
| SCHEMBL12216619 | 0.78 | — | — | |
| SCHEMBL20346810 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| EP-0329295-A1 | Renin inhibiting peptides with polar end groups | THE UPJOHN COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |