Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.53 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8162955 | 0.83 | ACKR3 (0.63) | TLR9TLR8TLR7ACKR3CHRM3 | |
| SCHEMBL14198241 | 0.82 | ACKR3 (0.53) | ACKR3CHRM3CCR2DRD2 | |
| SCHEMBL14574165 | 0.81 | CHRNB2 (0.63) | ADORA1PDE4BADORA2ATLR9TLR8 | |
| SCHEMBL13118285 | 0.80 | ACKR3 (0.61) | ACKR3CHRM3CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL10264922 | 0.80 | ACKR3 (0.52) | ADORA1PDE4BADORA2ATLR9TLR8 | |
| SCHEMBL10203245 | 0.79 | MEN1 (0.49) | ADORA1PDE4BADORA2ATLR9TLR8 | |
| SCHEMBL3034950 | 0.78 | BRAF (0.55) | TLR9TLR8TLR7ACKR3BRAF | |
| SCHEMBL3613268 | 0.78 | SLC2A1 (0.61) | CHRM3CHRNB2ACP1OPRK1CYP3A4 | |
| SCHEMBL12513651 | 0.78 | SLC5A7 (0.59) | ACKR3OPRK1 | |
| SCHEMBL1928910 | 0.76 | ERN1 (0.63) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032531-A1 | SPHINGOSINE KINASE INHIBITORS AND METHODS OF THEIR USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032531-A1 | SPHINGOSINE KINASE INHIBITORS AND METHODS OF THEIR USE | SPHK1, SPHK2, S1PR2 | ADORA1 2747/4885PDE4B 1052/4885ADORA2A 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.