Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140034 | 0.69 | — | — | |
| SCHEMBL1472570 | 0.68 | NISCH (0.42) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL3685297 | 0.67 | ADRA2A (0.45) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL3702761 | 0.66 | ADRA2A (0.48) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL26259985 | 0.65 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL26259965 | 0.62 | NISCH (0.54) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL9287236 | 0.62 | NISCH (0.64) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL28382846 | 0.61 | CSNK1A1 (0.56) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL27996777 | 0.61 | CSNK1A1 (0.42) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 | |
| SCHEMBL2652493 | 0.61 | MEN1 (0.47) | CSNK1A1TYRO3DYRK1BADRA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |