SCHEMBL5623960

SCHEMBL5623960

NCC(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10672557 0.97
SCHEMBL19343232 0.79 CETP (0.32)
SCHEMBL4425762 0.73
SCHEMBL11076884 0.71 AOC1 (0.31)
SCHEMBL15081202 0.69
SCHEMBL15403853 0.69
SCHEMBL19343225 0.69 CETP (0.32)
SCHEMBL727688 0.69
SCHEMBL6994682 0.69
SCHEMBL9945698 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
US-20240158335-A1 A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS University of Strasbourg (FR) 2024-05-16 US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP disclosed
WO-2022175132-A1 A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS BAYER AKTIENGESELLSCHAFT (DE) 2022-08-25 WO disclosed
EP-3152216-B1 BICYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-07-24 EP disclosed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US disclosed
EP-2892343-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS Bayer CropScience AG (DE) 2015-07-15 EP disclosed
WO-2014037349-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO disclosed
US-7189680-B2 5-halo-6-aryl[1,2,4]triazolo[1,5-a]pyrimidin-7-amines BAYER CROPSCIENCE AG (DE) 2007-03-13 US disclosed
US-20050222173-A1 Triazolopyrimidines BAYER CROPSCIENCE AG (DE) 2005-10-06 US disclosed
EP-1490370-A2 TRIAZOLOPYRIMIDINES Bayer CropScience Aktiengesellschaft (DE) 2004-12-29 EP disclosed
US-20040176398-A1 Triazolopyrimidines BAYER CROPSCIENCE AG (DE) 2004-09-09 US disclosed
WO-2003080614-A2 TRIAZOLOPYRIMIDINES USED AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-10-02 WO disclosed
US-4585569-A FLUOROALKYLAMINE AS WORKING FLUID IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-29 US disclosed
EP-0155423-A2 Heat pumps IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-25 EP disclosed
US-4541943-A FLUOROCARBON, FLUOROCARBON ETHER OR FLUOROALKYLAMINE FLUIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-17 US disclosed
EP-0030092-B1 GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-06 EP disclosed
EP-0127365-A2 Heat pumps IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-05 EP disclosed