SCHEMBL562435

SCHEMBL562435

O=S(=O)(O)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
TSHR P16473 5/20 0.42
HTT P42858 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
TDP1 Q9NUW8 1/20 0.35
CCR1 P32246 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PFKFB3 Q16875 1/20 0.33
LMNA P02545 1/20 0.33
CES1 P23141 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446435 0.98 TSHR (0.41) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL28230237 0.98 TSHR (0.41) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL11851180 0.98 TSHR (0.41) CYP3A4MAPK1TSHRHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL27285616 0.98 TSHR (0.41) CYP3A4MAPK1TSHRHTTSMN1; SMN2
Phosphine SCHEMBL8746307 0.98 TSHR (0.41) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL27577874 0.84 CYP2C9 (0.37) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL261900 0.82 MAPK1 (0.39) CYP3A4MAPK1TSHRHTTTDP1
SCHEMBL10532523 0.82 TSHR (0.40) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL27657206 0.82 CYP2C9 (0.36) CYP3A4MAPK1TSHRHTTSMN1; SMN2
SCHEMBL10424631 0.82 DPP4 (0.39) CYP3A4MAPK1TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115558272-A High-mechanical-property high-flow flame-retardant PC/ABS alloy material 浙江工业大学 2023-01-03 CN claimed
EP-3365168-B1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC (US) 2021-06-30 EP claimed
CN-108367529-B Lightweight flame retardant thermoplastic structures 施内勒公司 2021-02-05 CN claimed
EP-3237542-B1 POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE THEREOF, AND ARTICLES THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-18 EP claimed
CN-111154086-A Application of fluorine-containing compound as flame retardant in polyester PET and flame-retardant composition containing fluorine-containing compound 北京服装学院 2020-05-15 CN claimed
CN-111155194-A Flame-retardant anti-dripping PLLA and fiber thereof 北京服装学院 2020-05-15 CN claimed
CN-111154085-A Flame-retardant PET and fiber thereof 北京服装学院 2020-05-15 CN claimed
EP-2049583-B1 POLYSILOXANE COPOLYMERS,THERMOPLASTIC COMPOSITION, AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-11-06 EP claimed
EP-3365168-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES Schneller, LLC (US) 2018-08-29 EP claimed
US-20170113445-A1 LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES SCHNELLER LLC 2017-04-27 US claimed
US-4293628-A Electrophotographic elements containing disazo compounds RICOH CO., LTD. (JP) 1981-10-06 US claimed
US-4279981-A Electrophotographic elements containing trisazo compounds RICOH COMPANY, LTD. (JP) 1981-07-21 US claimed
US-4272598-A STYRYL DYES RICOH CO., LTD. (JP) 1981-06-09 US claimed
US-4260672-A Electrophotographic sensitive element having a photoconductive disazo pigment RICOH COMPANY, LTD. (JP) 1981-04-07 US claimed
US-4251614-A CARBAZOLE DERIVATIVES RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
US-4251613-A LAMINATE OF CONDUCTIVE SUPPORT AND PHOTOSENSITIVE LAYER RICOH COMPANY, LTD. (JP) 1981-02-17 US claimed
US-4251434-A ORGANIC SALTS OF ALKALINE AND ALKALINE EARTH METALS GENERAL ELECTRIC COMPANY (US) 1981-02-17 US claimed
EP-0016791-A4 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE. GEN ELECTRIC (US) 1980-10-15 EP claimed
EP-0016791-A1 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE GENERAL ELECTRIC COMPANY (US) 1980-10-15 EP claimed
WO-1980000084-A1 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE GEN ELECTRIC (US) 1980-01-24 WO claimed