SCHEMBL261900

SCHEMBL261900

O=S(=O)(O)c1ccc(Cl)c(Cl)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 3/20 0.37
CASP1 P29466 2/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
NSD2 O96028 1/20 0.35
MMP14 P50281 1/20 0.35
CASP6 P55212 1/20 0.35
DPP4 P27487 1/20 0.34
CES1 P23141 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CXCR2 P25025 2/20 0.33
HTT P42858 2/20 0.33
COMT P21964 1/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.33
PGAM1 P18669 1/20 0.33
AURKA O14965 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6755511 0.98 MAPK1 (0.38) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL184577 0.83 TRPV4 (0.40) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL10424631 0.83 DPP4 (0.39) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL562435 0.82 CYP3A4 (0.42) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL10957618 0.81 CA1 (0.50) MAPK1CYP3A4TSHRCA1CA2
SCHEMBL10446435 0.80 TSHR (0.41) MAPK1CYP3A4TSHRCASP1HSD17B10
Hydrochloric Acid SCHEMBL27285616 0.80 TSHR (0.41) MAPK1CYP3A4TSHRCASP1HSD17B10
Phosphine SCHEMBL8746307 0.80 TSHR (0.41) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL28230237 0.80 TSHR (0.41) MAPK1CYP3A4TSHRCASP1HSD17B10
SCHEMBL27577874 0.80 CYP2C9 (0.37) MAPK1CYP3A4TSHRCASP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115201186-B Detection test strip for detecting salivary uric acid and preparation method thereof 天宇华宏(北京)医学科技股份有限公司 2023-05-12 CN claimed
CN-115201186-A Test strip for detecting uric acid in saliva and preparation method thereof 天宇华宏(北京)医学科技股份有限公司 2022-10-18 CN claimed
US-20070020766-A1 Diagnosis of pre-eclampsia CYBERMED (U.K.) LIMITED (GB) 2007-01-25 US claimed
EP-1238099-A2 AUTOMATED LYSOPHOSPHOLIPID ASSAY AND METHODS OF DETECTING CANCER ABBOTT LABORATORIES (US) 2002-09-11 EP claimed
WO-2001032916-A2 AUTOMATED LYSOPHOSPHOLIPID ASSAY AND METHODS OF DETECTING CANCER ABBOTT LABORATORIES (US) 2001-05-10 WO claimed
US-5418142-A Glucose test strip for whole blood LIFESCAN, INC. (US) 1995-05-23 US claimed
US-5012015-A Nitrading a trichlorobenzene with mixed acid, hydrolysis DAIEI CHEMICAL CO., LTD. (JP) 1991-04-30 US claimed
EP-0415679-A2 Blood separation and analyte detection techniques LIFESCAN, INC. (US) 1991-03-06 EP claimed
JP-63074500-A None JP disclosed
CN-112626170-B Uric acid kit for rapidly and simply eliminating drug interference and preparation method thereof 中山标佳生物科技有限公司 2024-08-27 CN disclosed
CN-112522366-B Uric acid kit capable of eliminating interference of calcium dobesilate and phenol sulfoethylamine drugs in serum 中山标佳生物科技有限公司 2024-06-04 CN disclosed
CN-112662736-B Preparation method of uric acid kit for rapidly and simply eliminating interference of calcium dobesilate and phenol sulfoethylamine drugs in serum 中山标佳生物科技有限公司 2024-02-02 CN disclosed
CN-112522365-B Preparation method of uric acid kit capable of eliminating interference of calcium dobesilate and phenol sulfoethylamine drugs in serum 中山标佳生物科技有限公司 2023-12-26 CN disclosed
CN-112522364-B Uric acid kit for rapidly and simply eliminating interference of calcium dobesilate and phenol sulfoethylamine drugs in serum 中山标佳生物科技有限公司 2023-09-08 CN disclosed
EP-0193895-A2 An improved luminescent assay ABBOTT LABORATORIES (US) 1986-09-10 EP disclosed
EP-0078477-B1 FENCLOFENAC AS TBP BLOCKING AGENT IN IODOTHYRONINE IMMUNOASSAYS MILES LABORATORIES, INC. (US) 1986-09-10 EP disclosed
EP-0182225-A2 Enzymatic high range glucose test MILES INC. (US) 1986-05-28 EP disclosed
EP-0133464-A1 Iodothyronine immunoassays employing HMS as TBP blocking agent MILES LABORATORIES, INC. (US) 1985-02-27 EP disclosed
US-4468469-A Substituted phenylacetic acids and salts as TBP blocking agents in iodothyronine immunoassays MILES LABORATORIES, INC. (US) 1984-08-28 US disclosed
EP-0078477-A2 Fenclofenac as TBP blocking agent in iodothyronine immunoassays MILES LABORATORIES, INC. (US) 1983-05-11 EP disclosed