Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 4/20 | 0.59 |
| ▸ | BMP1 | P13497 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | PTGES | O14684 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624485 | 0.95 | KEAP1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5622632 | 0.89 | KEAP1 (0.64) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL20314689 | 0.89 | ESR1 (0.71) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5622498 | 0.83 | KEAP1 (0.68) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL5623048 | 0.82 | ESR1 (0.78) | ALOX5PTGESESR1L3MBTL1 | |
| SCHEMBL4827499 | 0.81 | MCHR1 (0.48) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29028430 | 0.79 | CNR2 (0.56) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL13979922 | 0.78 | CNR2 (0.61) | KEAP1CNR2BMP1LMNA | |
| SCHEMBL5622256 | 0.78 | ESR1 (0.68) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL6324195 | 0.78 | SMN1; SMN2 (0.65) | KEAP1NFE2L2CNR2BMP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021495-A1 | SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR | ESR1, ESR2, GPER1 | ALDH1A1 826/4885CYP3A4 95/4885CYP2C9 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.