Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29142282 | 0.90 | LMNA (0.46) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| SCHEMBL1461724 | 0.88 | LMNA (0.45) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| SCHEMBL16908415 | 0.88 | LMNA (0.45) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| Sulfuric Acid SCHEMBL21195053 | 0.88 | LMNA (0.45) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| SCHEMBL29459670 | 0.87 | LMNA (0.40) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| SCHEMBL193915 | 0.87 | LMNA (0.40) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| Sulfuric Acid SCHEMBL21195054 | 0.86 | GGPS1 (0.48) | LMNAGGPS1L3MBTL1PABPC1KMT2A | |
| SCHEMBL30140725 | 0.84 | LMNA (0.46) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL1880212 | 0.84 | LMNA (0.46) | LMNAKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL294294 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067571-B1 | SUPPLY DEVICE | HYDAC SYSTEMS & SERVICES GMBH (DE) | 2022-08-03 | — | — | EP | disclosed |
| US-20120034129-A1 | PRODUCTION METHOD FOR A METAL NANOSTRUCTURE USING AN IONIC LIQUID | SUH, KWANG SUCK (KR) | 2012-02-09 | — | — | US | disclosed |