Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.75 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.75 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676446 | 0.86 | PRSS1 (1.00) | PRSS1PRSS2PRSS3KMT2AWDR5 | |
| Hydrochloric Acid SCHEMBL9792863 | 0.86 | PRSS1 (0.83) | PRSS1PRSS2PRSS3KMT2AWDR5 | |
| Hydrochloric Acid SCHEMBL697893 | 0.84 | PRSS1 (0.96) | PRSS1PRSS2PRSS3KMT2AWDR5 | |
| SCHEMBL1715332 | 0.83 | PRSS1 (0.72) | PRSS1PRSS2PRSS3WDR5F2 | |
| SCHEMBL17696875 | 0.83 | PRSS1 (0.72) | PRSS1PRSS2PRSS3WDR5F2 | |
| SCHEMBL1788218 | 0.81 | PARP1 (0.62) | MEN1ESR1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL19608276 | 0.81 | MEN1 (0.59) | PRSS1PRSS2PRSS3MEN1ESR1 | |
| SCHEMBL23268275 | 0.78 | PRSS1 (0.71) | PRSS1PRSS2PRSS3WDR5F2 | |
| SCHEMBL7359286 | 0.77 | PARP1 (0.61) | PRSS1PRSS2PRSS3LMNAF2 | |
| SCHEMBL17774314 | 0.77 | PRSS1 (0.69) | PRSS1PRSS2PRSS3F2C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD (JP) | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | SLC7A1, NAT1, NACA | PRSS1 1149/4885PRSS2 1628/4885PRSS3 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.