Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.59 |
| ▸ | F2 | P00734 | 6/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.59 |
| ▸ | PLG | P00747 | 3/20 | 0.59 |
| ▸ | C1S | P09871 | 1/20 | 0.59 |
| ▸ | F12 | P00748 | 2/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3909792 | 0.98 | PRSS1 (0.63) | PARP1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL15547311 | 0.85 | PRSS1 (0.70) | PRSS1F2PRSS2PRSS3PLG | |
| Trifluoroacetic Acid SCHEMBL3316764 | 0.84 | PARP1 (0.55) | PARP1PRSS1F2PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL28555629 | 0.82 | PRSS1 (0.74) | PRSS1F2PRSS2PRSS3PLG | |
| Hydrochloric Acid SCHEMBL28253026 | 0.82 | PRSS1 (0.74) | PRSS1F2PRSS2PRSS3PLG | |
| SCHEMBL20937975 | 0.79 | PARP1 (0.53) | PARP1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL5626124 | 0.77 | PRSS1 (0.75) | PRSS1F2PRSS2PRSS3PLG | |
| SCHEMBL31747489 | 0.76 | PARP1 (1.00) | PARP1LMNABLMCA12CA1 | |
| Hydrochloric Acid SCHEMBL9792863 | 0.76 | PRSS1 (0.83) | PRSS1F2PRSS2PRSS3PLG | |
| SCHEMBL14515478 | 0.76 | PARP1 (0.61) | PARP1LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | claimed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | claimed |
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2015137408-A1 | METHOD FOR PRODUCING HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE, AND PRODUCTION INTERMEDIATE OF SAME | 味の素株式会社 | 2015-09-17 | — | — | WO | disclosed |
| CN-102993084-B | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA | 2015-05-20 | — | — | CN | disclosed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
| EP-0893437-A4 | TRYPTASE INHIBITOR AND NOVEL GUANIDINO DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997037969-A1 | TRYPTASE INHIBITOR AND NOVEL GUANIDINO DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-10-16 | — | — | WO | disclosed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, GRN | PARP1 2936/4885PRSS1 2062/4885F2 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.