Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5626789 | 0.79 | — | — | |
| SCHEMBL5628779 | 0.68 | — | — | |
| SCHEMBL5628817 | 0.67 | — | — | |
| SCHEMBL5630073 | 0.66 | IDH1 (0.40) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL5628838 | 0.65 | ALDH1A1 (0.41) | NPC1ALDH1A1GAAMAPTRAB9A | |
| Methane SCHEMBL9384299 | 0.64 | IDH1 (0.42) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL29047998 | 0.62 | HSP90AA1 (0.32) | — | |
| SCHEMBL5156626 | 0.60 | — | — | |
| SCHEMBL6623798 | 0.59 | — | — | |
| SCHEMBL8681926 | 0.59 | SMN1; SMN2 (0.38) | NPC1GAAMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | claimed |
| EP-1453817-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2004-09-08 | — | — | EP | claimed |
| WO-2003050096-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2003-06-19 | — | — | WO | claimed |
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | disclosed |
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | disclosed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | disclosed |
| EP-1453817-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050096-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | CYP51A1, DPM1, GMDS | NPC1 1034/4885ALDH1A1 362/4885GAA 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.