Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628871 | 1.00 | HIF1A (0.40) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5626872 | 0.91 | HIF1A (0.44) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5626881 | 0.91 | HIF1A (0.44) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5627288 | 0.89 | HIF1A (0.41) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5627285 | 0.89 | HIF1A (0.41) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5629070 | 0.85 | HIF1A (0.40) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5629060 | 0.85 | HIF1A (0.40) | HIF1AOPRL1HRH3SYK | |
| SCHEMBL5627792 | 0.83 | OPRL1 (0.32) | OPRL1SYK | |
| SCHEMBL5627797 | 0.83 | OPRL1 (0.32) | OPRL1SYK | |
| SCHEMBL5628828 | 0.83 | OPRL1 (0.35) | OPRL1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | disclosed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | disclosed |
| EP-1453817-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050096-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | CYP51A1, DPM1, GMDS | HIF1A 4700/4885OPRL1 4875/4885HRH3 4186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.