Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628878 | 0.83 | HIF1A (0.40) | OPRL1SYK | |
| SCHEMBL5627792 | 0.83 | OPRL1 (0.32) | OPRL1SYK | |
| SCHEMBL5628871 | 0.83 | HIF1A (0.40) | OPRL1SYK | |
| SCHEMBL5627797 | 0.83 | OPRL1 (0.32) | OPRL1SYK | |
| SCHEMBL5741744 | 0.77 | MEN1 (0.50) | MAPT | |
| SCHEMBL5742298 | 0.77 | KMT2A (0.51) | SMN1; SMN2RAB9AHSD17B10NPSR1MAPT | |
| SCHEMBL5743962 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2MAPT | |
| SCHEMBL5629225 | 0.74 | TP53 (0.32) | OPRL1SYKTP53HTTMAPT | |
| SCHEMBL5629230 | 0.74 | TP53 (0.32) | OPRL1SYKTP53HTTMAPT | |
| SCHEMBL5626872 | 0.73 | HIF1A (0.44) | OPRL1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | claimed |