Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.61 |
| ▸ | SMG1 | Q96Q15 | 6/20 | 0.61 |
| ▸ | CDK1 | P06493 | 4/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | BCR | P11274 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 6/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 4/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628905 | 0.91 | SMG1 (0.60) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5630619 | 0.82 | SMG1 (0.58) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5629919 | 0.82 | SMG1 (0.58) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5629170 | 0.82 | CDK2 (0.58) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5631594 | 0.82 | CDK2 (0.58) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5629124 | 0.81 | SMG1 (0.61) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL6093641 | 0.80 | SMG1 (0.66) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5629193 | 0.80 | SMG1 (0.63) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL6096290 | 0.79 | SMG1 (0.59) | CDK2SMG1CDK1ABL1BCR | |
| SCHEMBL5631482 | 0.79 | CDK2 (0.54) | CDK2SMG1CDK1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205301-B2 | Microbiocidal N-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205301-B2 | Microbiocidal N-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205301-B2 | Microbiocidal N-phenyl-n-[4-(4-pyridyl)-2-pyrimidin-2-yl]-amine derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1471786-B1 | MICROBIOCIDAL N-PHENYL-N- 4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL|-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| US-20050085496-A1 | Microbiocidal n-phenyl-n-{4-(4-pyridyl)-2-pyrimidin-2-yl}-amine derivatives | SYNGENTA CROP PROTECTION, INC. | 2005-04-21 | — | — | US | disclosed |
| EP-1471786-A1 | MICROBIOCIDAL N-PHENYL-N- 4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | Syngenta Participations AG (CH) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003047347-A1 | MICROBIOCIDAL N-PHENYL-N-[4-(4-PYRIDYL)-2-PYRIMIDIN-2-YL]-AMINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085496-A1 | Microbiocidal n-phenyl-n-{4-(4-pyridyl)-2-pyrimidin-2-yl}-amine derivatives | MSR1, SIGMAR1, CYP2A13 | CDK2 4068/4885SMG1 3758/4885CDK1 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.