Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | FLT3 | P36888 | 5/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629622 | 0.91 | NPC1 (0.52) | ADORA3HTR2CHTR2BFLT3ADORA1 | |
| SCHEMBL5626392 | 0.91 | FLT3 (0.55) | ADORA3HTR2CHTR2BFLT3ADORA1 | |
| SCHEMBL5196709 | 0.85 | NPC1 (0.49) | ADORA3FLT3ADORA1NPC1ADORA2A | |
| SCHEMBL5626699 | 0.83 | PDGFRA (0.67) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL5626704 | 0.83 | PDGFRA (0.67) | FLT3PDGFRACDK2SRCCCNE1 | |
| Ethyl Acetate SCHEMBL5628994 | 0.83 | SRC (0.54) | ADORA3HTR2CHTR2BFLT3ADORA1 | |
| Hydrochloric Acid SCHEMBL5195206 | 0.82 | PDGFRA (0.66) | FLT3PDGFRACDK2SRCCCNE1 | |
| Hydrochloric Acid SCHEMBL5195210 | 0.82 | PDGFRA (0.66) | FLT3PDGFRACDK2SRCCCNE1 | |
| SCHEMBL5627809 | 0.81 | NPC1 (0.55) | ADORA3FLT3NPC1PDGFRACDK2 | |
| SCHEMBL5627099 | 0.81 | ADORA3 (0.57) | ADORA3HTR2CHTR2BADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208598-B2 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | AVENTIS PHARMA (FR) | 2007-04-24 | — | — | US | disclosed |
| US-7122669-B1 | Purine derivatives, preparation method and pharmaceutical compositions containing same | HOECHST MARION ROUSSEL (FR) | 2006-10-17 | — | — | US | disclosed |
| US-20050187228-A1 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187228-A1 | Derivatives of purine, their preparation process and pharmaceutical compositions containing them | CDK6, CDK1, CDK2 | ADORA3 320/4885HTR2C 3231/4885HTR2B 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.