Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.69 |
| ▸ | CTSK | P43235 | 6/20 | 0.69 |
| ▸ | CTSB | P07858 | 5/20 | 0.69 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584535 | 1.00 | CTSS (0.69) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL5844919 | 0.92 | CTSS (0.64) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL16460248 | 0.90 | CTSS (0.66) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL10094314 | 0.90 | CTSS (0.66) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL15808276 | 0.89 | CTSS (0.56) | CTSSCTSKCTSBKLK5PTPN1 | |
| SCHEMBL1519731 | 0.89 | CTSS (0.74) | CTSSCTSKCTSBPTPN1CTSL | |
| SCHEMBL3821361 | 0.89 | CTSS (0.74) | CTSSCTSKCTSBPTPN1CTSL | |
| SCHEMBL29397962 | 0.89 | CTSS (0.74) | CTSSCTSKCTSBPTPN1CTSL | |
| SCHEMBL29481445 | 0.89 | CTSS (0.74) | CTSSCTSKCTSBPTPN1CTSL | |
| SCHEMBL29436862 | 0.89 | CTSS (0.74) | CTSSCTSKCTSBPTPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185128-A1 | Compounds and compositions for treating obesity | NOVO NORDISK A/S (DK) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185128-A1 | Compounds and compositions for treating obesity | MC4R, MC5R, MC3R | CTSS 3100/4885CTSK 2333/4885CTSB 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.