Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474198 | 0.91 | IMPDH2 (0.76) | IMPDH2 | |
| SCHEMBL1475938 | 0.84 | IMPDH2 (0.81) | IMPDH2 | |
| SCHEMBL1473010 | 0.82 | IMPDH2 (1.00) | IMPDH2 | |
| SCHEMBL1473597 | 0.80 | IMPDH2 (0.65) | IMPDH2 | |
| SCHEMBL1473463 | 0.79 | IMPDH2 (0.74) | IMPDH2 | |
| SCHEMBL1475776 | 0.77 | IMPDH2 (0.78) | IMPDH2 | |
| SCHEMBL1473618 | 0.74 | IMPDH2 (0.83) | IMPDH2 | |
| SCHEMBL1476225 | 0.74 | IMPDH2 (0.85) | IMPDH2 | |
| SCHEMBL1473908 | 0.73 | IMPDH2 (0.73) | IMPDH2 | |
| SCHEMBL5630245 | 0.73 | POLB (0.39) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786415-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006017896-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-02-23 | — | — | WO | disclosed |
| US-6399773-B1 | AUTOIMMUNE DISEASE; TRANSPLANTING ORGANS | BRISTOL-MYERS SQUIBB CO. | 2002-06-04 | — | — | US | disclosed |