SCHEMBL563099

SCHEMBL563099

O=P(Cc1ccccc1)(Cc1ccccc1)Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HTT P42858 1/20 0.53
SRC P12931 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
ANPEP P15144 1/20 0.47
LAP3 P28838 1/20 0.47
HPGD P15428 1/20 0.47
KLK8 O60259 1/20 0.46
PLAU P00749 1/20 0.46
KLK2 P20151 1/20 0.46
KLK4 Q9Y5K2 1/20 0.46
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7772939 0.90 HTT (0.46) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL563232 0.83 KLK8 (0.63) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL7770131 0.83 MEN1 (0.50) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL20826937 0.79 HPGD (0.52) MEN1KMT2AHTTHPGDLMNA
SCHEMBL3836998 0.79 SRC (0.57) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL1967085 0.78 L3MBTL1 (0.53) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL24359440 0.78 KLK8 (0.41) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL777179 0.77 L3MBTL1 (0.59) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL17923914 0.76 KLK8 (0.53) MEN1KMT2AHTTSRCL3MBTL1
SCHEMBL563403 0.76 MEN1 (0.51) MEN1KMT2AHTTL3MBTL1LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1876193-B1 PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER MITSUBISHI GAS CHEMICAL CO (JP) 2013-12-25 EP disclosed
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition SAKAMOTO JUN (JP) 2012-02-09 US disclosed
US-7897672-B2 Process for producing polyoxymethylene copolymer MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-03-01 US disclosed
US-20100209735-A1 Polyester resin compositions, polyester film, and magnetic recording medium YOSHIMURA HITOSHI 2010-08-19 US disclosed
US-7709594-B2 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2010-05-04 US disclosed
US-20090062503-A1 Process for Producing Polyoxymethylene Copolymer MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-03-05 US disclosed
EP-1876193-A1 PROCESS FOR PRODUCING POLYOXYMETHYLENE COPOLYMER MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-01-09 EP disclosed
US-20050239929-A1 Polyester resin compositions, catalyst for polyester production, polyester film, and magnetic recording medium TORAY INDUSTRIES, INC. (JP) 2005-10-27 US disclosed
EP-1550683-A1 POLYESTER RESIN COMPOSITIONS, CATALYST FOR POLYESTER PRODUCTION, POLYESTER FILM, AND MAGNETIC RECORDING MEDIUM TORAY INDUSTRIES, INC. (JP) 2005-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120034480-A1 Catalyst for producing polyesters and polyester resin composition PUF60, RPS24, SRP54 MEN1 2460/4885KMT2A 1503/4885HTT 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.