⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629632 | 0.89 | — | — | |
| SCHEMBL2403860 | 0.81 | — | — | |
| SCHEMBL14353453 | 0.76 | — | — | |
| SCHEMBL4333110 | 0.73 | MGLL (0.42) | — | |
| Ethylenediamine SCHEMBL4788800 | 0.73 | ODC1 (0.32) | — | |
| SCHEMBL2833548 | 0.72 | — | — | |
| SCHEMBL224505 | 0.72 | MEN1 (0.58) | — | |
| SCHEMBL10252502 | 0.71 | — | — | |
| SCHEMBL4322351 | 0.71 | — | — | |
| SCHEMBL11026621 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558461-B1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | BRISTOL MYERS SQUIBB CO (US) | 2015-12-02 | — | — | EP | disclosed |
| US-7285572-B2 | CaSR antagonist | JAPAN TOBACCO INC. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20060135572-A1 | CaSR antagonist | JAPAN TOBACCO INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1630157-A1 | CaSR ANTAGONIST | JAPAN TOBACCO INC. (JP) | 2006-03-01 | — | — | EP | disclosed |
| CN-1040543-C | Amidation catalyst concentrates | DU PONT (US) | 1998-11-04 | — | — | CN | disclosed |
| EP-0353969-A1 | Catalytic amidation process | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0057441-B1 | MIXED ETHER COMPOSITIONS CONTAINING OLIGOMERS OF POLYFUNCTIONAL PHOSPHINE OXIDES AND METHOD FOR THEIR MANUFACTURE | FMC Corporation (US) | 1985-09-11 | — | — | EP | disclosed |
| US-4377653-A | Mixed ether compositions containing oligomers of polyfunctional phosphine oxides: flame retardants for polymers | FMC CORPORATION (US) | 1983-03-22 | — | — | US | disclosed |
| EP-0057441-A2 | Mixed ether compositions containing oligomers of polyfunctional phosphine oxides and method for their manufacture | FMC Corporation (US) | 1982-08-11 | — | — | EP | disclosed |
| US-4052486-A | PROCESS FOR PREPARING CYCLIC PHOSPHINIC ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |