Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221846 | 0.83 | DPP4 (0.43) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL5632087 | 0.77 | DPP4 (0.37) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL14572688 | 0.71 | DPP4 (0.70) | DPP4DPP7FAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5224457 | 0.70 | DPP4 (0.69) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL5219023 | 0.68 | DPP4 (0.52) | DPP4DPP7PPARGPPARAFAP | |
| SCHEMBL23997549 | 0.65 | DPP4 (0.53) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL2036339 | 0.65 | DPP4 (0.53) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL6430514 | 0.65 | DPP4 (0.53) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL12891267 | 0.65 | EPHX1 (0.51) | DPP4DPP7EPHX1ACEPPARG | |
| SCHEMBL1254390 | 0.64 | KMT2A (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196201-B2 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |