Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5221846 | 0.90 | DPP4 (0.43) | DPP4DPP7ACEPPARGPPARA | |
| SCHEMBL5632086 | 0.77 | DPP4 (0.42) | DPP4DPP7ACEPPARGPPARA | |
| SCHEMBL5219023 | 0.75 | DPP4 (0.52) | DPP4DPP7PPARGPPARA | |
| SCHEMBL1254391 | 0.66 | KMT2A (0.48) | ALDH1A1LMNA | |
| SCHEMBL14572688 | 0.66 | DPP4 (0.70) | DPP4DPP7 | |
| SCHEMBL5220123 | 0.66 | DPP4 (0.61) | DPP4DPP7PREP | |
| Hydrochloric Acid SCHEMBL5224457 | 0.65 | DPP4 (0.69) | DPP4DPP7 | |
| SCHEMBL6828636 | 0.64 | DPP4 (0.75) | DPP4DPP7 | |
| SCHEMBL3150545 | 0.64 | DPP4 (0.75) | DPP4DPP7 | |
| SCHEMBL5711277 | 0.63 | CAPN1 (0.48) | DPP4ACEALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196201-B2 | Pyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-27 | — | — | US | disclosed |