Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261536 | 0.97 | BMP1 (0.45) | BMP1LMNABACE1ALDH1A1TSHR | |
| SCHEMBL6260340 | 0.94 | BMP1 (0.48) | BMP1LMNABACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6260176 | 0.92 | BMP1 (0.39) | BMP1LMNABACE1ALDH1A1TSHR | |
| SCHEMBL5633798 | 0.90 | BACE1 (0.42) | BMP1BACE1SMN1; SMN2MMP2MMP13 | |
| SCHEMBL5633526 | 0.90 | BACE1 (0.43) | BMP1BACE1ALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL5634518 | 0.89 | BACE1 (0.42) | BMP1LMNABACE1ALDH1A1TSHR | |
| SCHEMBL7243370 | 0.89 | BACE1 (0.42) | BMP1LMNABACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5634147 | 0.88 | BACE1 (0.41) | BMP1BACE1SMN1; SMN2MMP2MMP13 | |
| SCHEMBL14367269 | 0.85 | SPPL2A (0.46) | BMP1LMNA | |
| SCHEMBL5173543 | 0.83 | BACE1 (0.43) | BMP1LMNABACE1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | claimed |
| US-20060199822-A1 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2006-09-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199822-A1 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | PRSS1, DNPEP, PREP | BMP1 3507/4885LMNA 3038/4885BACE1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.