Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.68 |
| ▸ | CES2 | O00748 | 5/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651766 | 0.97 | CES1 (0.72) | CES1CES2PAOXTSHRLMNA | |
| SCHEMBL5049781 | 0.90 | CES1 (0.72) | CES1CES2TSHRALDH1A1SLC22A6 | |
| SCHEMBL1171470 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL1727904 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL31737664 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL9857091 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL7229888 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL10582661 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL2567828 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD | |
| SCHEMBL11671856 | 0.89 | CES1 (0.80) | CES1CES2TSHRPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287836-A1 | Method for Preparing Compounds Comprising Cucurbituril Groups | ACSL6, AGL, LIPA | CES1 896/4885CES2 73/4885PAOX 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.