Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.72 |
| ▸ | CES2 | O00748 | 6/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633290 | 0.97 | CES1 (0.68) | CES1CES2ALDH1A1TSHRPAOX | |
| SCHEMBL5049781 | 0.93 | CES1 (0.72) | CES1CES2CA4ALDH1A1TSHR | |
| SCHEMBL27441411 | 0.91 | CES1 (0.62) | CES1CES2CA4ALDH1A1PAOX | |
| SCHEMBL4645240 | 0.88 | CES1 (0.59) | CES1CES2ALDH1A1TSHRPAOX | |
| SCHEMBL146633 | 0.88 | CES1 (0.84) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL7229888 | 0.86 | CES1 (0.80) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL10582661 | 0.86 | CES1 (0.80) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL11671856 | 0.86 | CES1 (0.80) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL2567828 | 0.86 | CES1 (0.80) | CES1CES2ALDH1A1TSHR | |
| SCHEMBL8458714 | 0.86 | CES1 (0.80) | CES1CES2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |