Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.61 |
| ▸ | FLT4 | P35916 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051982 | 0.88 | MEN1 (0.77) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL9637653 | 0.88 | MEN1 (0.77) | RAB9ANPC1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29388210 | 0.86 | MEN1 (0.74) | RAB9ANPC1MEN1KMT2ALMNA | |
| Bromide SCHEMBL29417998 | 0.86 | MEN1 (0.74) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL10665495 | 0.83 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL30633570 | 0.81 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL8663578 | 0.81 | RAB9A (0.63) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL7785654 | 0.81 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL19932355 | 0.81 | RAB9A (0.71) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL30504811 | 0.80 | RAB9A (0.89) | RAB9ANPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253197-B2 | Aminothiazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |