Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PRCP | P42785 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635539 | 0.90 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL5634369 | 0.90 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL5634527 | 0.89 | CCR5 (0.66) | CCR5KCNH2PRCP | |
| SCHEMBL14514138 | 0.86 | CCR5 (0.65) | CCR5KCNH2PRCP | |
| SCHEMBL5634195 | 0.86 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL5634497 | 0.86 | CCR5 (0.65) | CCR5KCNH2PRCP | |
| SCHEMBL5634997 | 0.86 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL5660911 | 0.85 | CCR5 (0.68) | CCR5KCNH2 | |
| SCHEMBL5660917 | 0.85 | CCR5 (0.68) | CCR5KCNH2 | |
| SCHEMBL5633948 | 0.85 | CCR5 (0.64) | CCR5KCNH2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | claimed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20010039026-A1 | Assay method | PFIZER INC. | 2001-11-08 | — | — | US | disclosed |
| EP-1118858-A2 | Assay method | Pfizer Limited (GB) | 2001-07-25 | — | — | EP | disclosed |