Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795768 | 0.85 | DRD3 (0.42) | DRD3DRD2ITGB3ITGA2B | |
| SCHEMBL4795276 | 0.84 | DRD3 (0.39) | DRD3DRD2ITGB3 | |
| SCHEMBL4795316 | 0.83 | DRD3 (0.43) | DRD3DRD2 | |
| SCHEMBL4792614 | 0.83 | DRD3 (0.41) | DRD3DRD2 | |
| SCHEMBL4778922 | 0.80 | HDAC6 (0.47) | CYP2D6CYP1A2DRD3OPRM1OPRK1 | |
| SCHEMBL5634701 | 0.80 | CYP2D6 (0.41) | CYP2D6ALDH1A1CYP1A2DRD3DRD2 | |
| SCHEMBL4794868 | 0.79 | DRD3 (0.41) | DRD3DRD2 | |
| SCHEMBL5935169 | 0.79 | MCHR1 (0.39) | DRD3DRD2ITGB3ITGA2B | |
| SCHEMBL4792233 | 0.78 | DRD3 (0.44) | DRD3DRD2ITGB3ITGA2B | |
| SCHEMBL4794024 | 0.77 | DRD3 (0.42) | DRD3OPRK1DRD2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |