Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795775 | 0.83 | HTR1D (0.44) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL4795282 | 0.82 | HTR1D (0.40) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL4792617 | 0.81 | HTR1D (0.43) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL4795321 | 0.81 | HTR1D (0.51) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL5633617 | 0.80 | HDAC6 (0.43) | CYP2D6CYP1A2HTR1DHTR1BDRD2 | |
| SCHEMBL5634698 | 0.80 | CYP2D6 (0.39) | CYP2D6ALDH1A1CYP1A2DRD2DRD3 | |
| SCHEMBL4794873 | 0.79 | CA1 (0.40) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL5935175 | 0.78 | HTR1D (0.40) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL20884062 | 0.77 | HTR1D (0.48) | HTR1DHTR1BDRD2DRD3DRD4 | |
| SCHEMBL4792237 | 0.76 | CA1 (0.40) | HTR1DHTR1BDRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |