⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793050 | 0.64 | PRKCA (0.37) | — | |
| Hydrochloric Acid SCHEMBL772835 | 0.61 | PRKCA (0.49) | — | |
| SCHEMBL14572903 | 0.60 | PRKCA (0.37) | — | |
| SCHEMBL793054 | 0.60 | PRKCA (0.35) | — | |
| SCHEMBL804702 | 0.60 | PRKCA (0.34) | — | |
| SCHEMBL792795 | 0.59 | PRKCA (0.38) | — | |
| SCHEMBL771459 | 0.57 | PRKCA (0.51) | — | |
| SCHEMBL13476308 | 0.56 | NR1H4 (0.35) | — | |
| SCHEMBL803765 | 0.56 | PRKCA (0.35) | — | |
| SCHEMBL13476675 | 0.56 | HRH3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049593-A1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2007-03-01 | — | — | US | disclosed |