Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.67 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320505 | 0.87 | CYP19A1 (0.59) | NR1H2NR1H3 | |
| SCHEMBL15727387 | 0.86 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL14367891 | 0.85 | NR1H2 (0.75) | NR1H2NR1H3 | |
| SCHEMBL2884571 | 0.84 | NR1H2 (0.52) | NR1H2NR1H3 | |
| SCHEMBL17220643 | 0.84 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL26670152 | 0.84 | NR1H2 (0.74) | NR1H2NR1H3 | |
| SCHEMBL17220651 | 0.83 | NR1H2 (0.72) | NR1H2NR1H3 | |
| SCHEMBL31282085 | 0.83 | NR1H2 (0.72) | NR1H2NR1H3 | |
| SCHEMBL19181944 | 0.83 | NR1H2 (0.72) | NR1H2NR1H3 | |
| SCHEMBL17220658 | 0.83 | NR1H2 (0.72) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | US | disclosed |
| EP-1689710-A1 | INDOLE DERIVATIVES FOR USE AS CHEMICAL UNCOUPLER | NOVO NORDISK A/S (DK) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005051908-A1 | INDOLE DERIVATIVES FOR USE AS CHEMICAL UNCOUPLER | NOVO NORDISK A/S (DK) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010559-A1 | Indole derivatives for use as chemical uncoupler | GPR119, IDO2, IDO1 | NR1H2 3126/4885NR1H3 3380/4885CA12 4375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.