Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 18/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634673 | 0.95 | CFTR (0.52) | CFTRKMT2A | |
| SCHEMBL6003860 | 0.95 | CFTR (0.52) | CFTRKMT2A | |
| Trifluoroacetic Acid SCHEMBL5661939 | 0.94 | CFTR (0.47) | CFTRKMT2ACDK8NTRK3 | |
| Trifluoroacetic Acid SCHEMBL5635177 | 0.92 | CFTR (0.46) | CFTRKMT2ACDK8NTRK3 | |
| Trifluoroacetic Acid SCHEMBL6279088 | 0.90 | CFTR (0.49) | CFTRCDK8NTRK3 | |
| SCHEMBL6003560 | 0.89 | CFTR (0.51) | CFTRKMT2ACDK8NTRK3 | |
| SCHEMBL5635489 | 0.89 | CFTR (0.51) | CFTRKMT2ACDK8NTRK3 | |
| Trifluoroacetic Acid SCHEMBL5635107 | 0.89 | CFTR (0.43) | CFTRKMT2ACDK8NTRK3 | |
| SCHEMBL6003573 | 0.88 | CFTR (0.53) | CFTRKMT2A | |
| SCHEMBL5635694 | 0.88 | CFTR (0.53) | CFTRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004765-A1 | New compounds | BIOVITRUM AB (SE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004765-A1 | New compounds | GHSR, GIPR, PRLHR | CFTR 519/4885KMT2A 3641/4885CDK8 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.