Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.53 |
| ▸ | HTR2A | P28223 | 8/20 | 0.49 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5636295 | 1.00 | HTR2C (0.53) | HTR2CHTR2AHTR2BL3MBTL1KDM4E | |
| SCHEMBL6756313 | 0.93 | HTR2C (0.53) | HTR2CHTR2AHTR2BL3MBTL1KDM4E | |
| SCHEMBL5636494 | 0.88 | HTR2C (0.58) | HTR2CHTR2AHTR2BDRD2RYR2 | |
| SCHEMBL5637051 | 0.88 | HTR2C (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL5636533 | 0.88 | HTR2C (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL5636382 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2BL3MBTL1DRD2 | |
| SCHEMBL5636083 | 0.87 | HTR2C (0.37) | HTR2CHTR2AHTR2BL3MBTL1DRD2 | |
| SCHEMBL5636128 | 0.86 | HTR2C (0.57) | HTR2CHTR2AHTR2BKDM4EDRD2 | |
| SCHEMBL5636580 | 0.85 | HTR2C (0.58) | HTR2CHTR2AHTR2BDRD2RYR2 | |
| SCHEMBL5636958 | 0.84 | HTR2C (0.62) | HTR2CHTR2AHTR2BKMT2ARYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39679-E1 | Substituted heterocycle fused gamma-carbolines | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-06-05 | — | — | US | disclosed |