Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.37 |
| ▸ | HTR2A | P28223 | 17/20 | 0.36 |
| ▸ | DRD2 | P14416 | 16/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5636382 | 1.00 | HTR2C (0.37) | HTR2CHTR2ADRD2HTR2BL3MBTL1 | |
| SCHEMBL6756112 | 0.91 | ALDH1A1 (0.35) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5636571 | 0.91 | ALDH1A1 (0.35) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5636495 | 0.91 | HTR2C (0.40) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5635426 | 0.89 | HTR2C (0.39) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5636454 | 0.89 | HTR2C (0.39) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5636295 | 0.87 | HTR2C (0.53) | HTR2CHTR2ADRD2HTR2BL3MBTL1 | |
| SCHEMBL5637552 | 0.87 | HTR2C (0.53) | HTR2CHTR2ADRD2HTR2BL3MBTL1 | |
| SCHEMBL5636867 | 0.86 | KDM4E (0.41) | HTR2CHTR2ADRD2HTR2B | |
| SCHEMBL5635056 | 0.85 | HTR2C (0.46) | HTR2CHTR2ADRD2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39679-E1 | Substituted heterocycle fused gamma-carbolines | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-06-05 | — | — | US | disclosed |