⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236961 | 0.76 | — | — | |
| SCHEMBL7028793 | 0.76 | — | — | |
| SCHEMBL3390649 | 0.73 | — | — | |
| SCHEMBL8568515 | 0.67 | ALDH1A1 (0.40) | — | |
| SCHEMBL4475986 | 0.67 | — | — | |
| SCHEMBL2018201 | 0.64 | — | — | |
| SCHEMBL503396 | 0.64 | — | — | |
| SCHEMBL6223 | 0.64 | — | — | |
| SCHEMBL8679785 | 0.64 | ALDH1A1 (1.00) | — | |
| SCHEMBL16236787 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428426-B2 | Process and intermediates for preparing a JAK1 inhibitor | INCYTE CORPORATION (US) | 2025-09-30 | — | — | US | claimed |
| US-11905292-B2 | Process and intermediates for preparing a JAK inhibitor | INCYTE CORPORATION (US) | 2024-02-20 | — | — | US | claimed |
| US-11897889-B2 | Process and intermediates for preparing a JAK1 inhibitor | INCYTE CORPORATION (US) | 2024-02-13 | — | — | US | claimed |
| CN-117043152-A | Methods and intermediates for preparing JAK1 inhibitors | 因赛特公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116761792-A | Methods and intermediates for preparing JAK inhibitors | 因赛特公司 | 2023-09-15 | — | — | CN | claimed |
| EP-4200278-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK1 INHIBITOR | Incyte Corporation (US) | 2023-06-28 | — | — | EP | claimed |
| EP-4200300-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK INHIBITOR | Incyte Corporation (US) | 2023-06-28 | — | — | EP | claimed |
| US-20220056034-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK1 INHIBITOR | INCYTE CORPORATION | 2022-02-24 | — | — | US | claimed |
| WO-2022040172-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK1 INHIBITOR | INCYTE CORPORATION (US) | 2022-02-24 | — | — | WO | claimed |
| WO-2022040180-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK INHIBITOR | INCYTE CORPORATION (US) | 2022-02-24 | — | — | WO | claimed |
| US-20220056035-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK INHIBITOR | INCYTE CORPORATION | 2022-02-24 | — | — | US | claimed |
| CN-109678662-A | A kind of synthetic method of 12 carbon of acetic acid 7E, 9Z-, two enester | 云南大学 | 2019-04-26 | — | — | CN | claimed |
| CN-109563098-A | The method for preparing chloro- 7H- pyrrolo- [2,3-d] pyrimidine of 4- | 斯福瑞（南通）制药有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-108929206-A | A method of the activation bromo- 1,1- dimethoxy-ethane of 2- | 盐城市胜达化工有限公司 | 2018-12-04 | — | — | CN | claimed |
| US-20260042768-A1 | PROCESS AND INTERMEDIATES FOR PREPARING A JAK INHIBITOR | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| US-12479851-B2 | Process and intermediates for preparing a JAK inhibitor | INCYTE CORPORATION (US) | 2025-11-25 | — | — | US | disclosed |
| US-12428426-B2 | Process and intermediates for preparing a JAK1 inhibitor | INCYTE CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| CN-1032207-C | Imidazopyrazole derivatives useful as analgesics and anti-inflammatory agents | SANKYO CO (JP) | 1996-07-03 | — | — | CN | disclosed |
| CN-1094049-A | Be used as the preparation method of the imidazolopyrazole derivatives of anodyne and antiphlogistic | SANKYO CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| CN-1040196-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO CO (JP) | 1990-03-07 | — | — | CN | disclosed |