⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetamide SCHEMBL142 | 0.96 | — | — | |
| Trifluoroacetamide SCHEMBL27678123 | 0.96 | LMNA (0.42) | — | |
| Trifluoroacetamide SCHEMBL9533719 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL11737106 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL30137201 | 0.92 | LMNA (0.39) | — | |
| Trifluoroacetamide SCHEMBL6982843 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL15993978 | 0.92 | LMNA (0.50) | — | |
| Trifluoroacetamide SCHEMBL3655478 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL16269134 | 0.92 | — | — | |
| Trifluoroacetamide SCHEMBL7953427 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463000-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023137309-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| WO-2016120808-A1 | HETEROARYLAMINOISOQUINOLINES, METHODS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | MINORYX THERAPEUTICS S.L. (ES) | 2016-08-04 | — | — | WO | disclosed |
| US-20160168132-A1 | DI(HETERO)ARYLAMIDES AND SULFONAMIDES, METHODS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | MINORYX THERAPEUTICS S.L. (ES) | 2016-06-16 | — | — | US | disclosed |
| EP-3027590-A1 | DI(HETERO)ARYLAMIDES AND SULFONAMIDES, METHODS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Minoryx Therapeutics S.L. (ES) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014900-A1 | DI(HETERO)ARYLAMIDES AND SULFONAMIDES, METHODS FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | MINORYX THERAPEUTICS S.L. (ES) | 2015-02-05 | — | — | WO | disclosed |
| US-20070155731-A1 | Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity | MERCK SHARP & DOHME CORP. | 2007-07-05 | — | — | US | disclosed |
| EP-1718152-A2 | AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005072361-A2 | AMINOCYCLOPENTYL PYRIDOPYRAZINONE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20040058364-A1 | Modified nucleotides and methods useful for nucleic acid sequencing | INVITROGEN CORPORATION | 2004-03-25 | — | — | US | disclosed |
| WO-1999049082-A2 | MODIFIED NUCLEOTIDES AND METHODS USEFUL FOR NUCLEIC ACID SEQUENCING | INVITROGEN CORPORATION (US) | 1999-09-30 | — | — | WO | disclosed |