Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | EDNRA | P25101 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29242598 | 0.84 | CA2 (0.67) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL1131010 | 0.83 | CA2 (0.71) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL9019311 | 0.83 | CA2 (0.71) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL10344363 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11948494 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL3116246 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL133520 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL108421 | 0.81 | CA2 (1.00) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL109002 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL21283 | 0.81 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308608-A | Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 | ABBOTT LAB (US) | 2001-08-15 | — | — | CN | claimed |
| EP-0650595-A4 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF. | PATCHORNIK ZIPORA (IL) | 1996-08-21 | — | — | EP | claimed |
| EP-0451824-B1 | Chelating compounds and their use | NIHON MEDIPHYSICS CO LTD (JP) | 1996-02-14 | — | — | EP | claimed |
| US-5472628-A | Aryl boronic acid | THE PROCTER & GAMBLE COMPANY (US) | 1995-12-05 | — | — | US | claimed |
| EP-0650595-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, Zipora (IL) | 1995-05-03 | — | — | EP | claimed |
| US-5298197-A | Chemiluminescent microemulsions | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1994-03-29 | — | — | US | claimed |
| WO-1994001771-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, ZIPORA (IL) | 1994-01-20 | — | — | WO | claimed |
| US-4540548-A | Method of detecting fluorescent materials and apparatus for their detection | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| US-20230181518-A1 | PREVENTION OF ROSACEA INFLAMMATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-15 | — | — | US | disclosed |
| US-11607458-B2 | Enrichment-triggered chemical delivery system | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-03-21 | — | — | US | disclosed |
| US-20220412917-A1 | Dual Mode Scanning Optical System for Capillary Electrophoresis | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2022-12-29 | — | — | US | disclosed |
| US-11382890-B2 | Prevention of rosacea inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-07-12 | — | — | US | disclosed |
| CN-113797905-B | Pyridine dicarboxamide bridged bis-beta-cyclodextrin stationary phase and preparation method and application thereof | 南昌大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-114729915-A | Dual-mode scanning optical system for capillary electrophoresis | DH科技发展私人贸易有限公司 | 2022-07-08 | — | — | CN | disclosed |
| US-4540548-A | Method of detecting fluorescent materials and apparatus for their detection | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0116472-A2 | Antigenic materials | COUNCIL OF GOVERNORS OF THE UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST. THOMAS'S HOSPITALS (GB) | 1984-08-22 | — | — | EP | disclosed |
| US-4447356-A | CYCLIC POLYPEPTIDES; MOLLUSC VENOMS; ANTICHOLINERGIC AGENTS; NERVOUS SYSTEM DISORDERS | OLIVERA BALDOMERO M | 1984-05-08 | — | — | US | disclosed |
| US-4419452-A | Method of detecting fluorescent materials and apparatus for their detection | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-12-06 | — | — | US | disclosed |
| US-4378500-A | LIQUID CHROMATOGRAPHY WITH POLAR SOLVENT | VARIAN ASSOCIATES, INC. (US) | 1983-03-29 | — | — | US | disclosed |
| US-4305872-A | HYPOTHALAMIC RELEASING AND INHIBITORY FACTORS, ENKEPHALINS AND ANTAGONISTS TO PRECURSOR PEPTIDES USEFUL IN BIOASSAY | Wingrove, Kenneth (US) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11607458-B2 | Enrichment-triggered chemical delivery system | HMGB1, PAICS, CCL2 | CA2 2880/4885CYP1A2 1176/4885CYP2C19 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.