D-Glutamate

D-Glutamate

SCHEMBL563907

NC(CCC(=O)O)C(=O)O.NC(N)=O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.90
GRM6 O15303 2/20 0.90
GRM7 Q14831 2/20 0.90
GRM4 Q14833 2/20 0.90
GSR P00390 2/20 0.90
GRIN2D O15399 1/20 0.90
GRIN3B O60391 1/20 0.90
CYP1A2 P05177 1/20 0.90
GRIK1 P39086 1/20 0.90
GRM5 P41594 1/20 0.90
GRIA1 P42261 1/20 0.90
GRIA2 P42262 1/20 0.90
GRIA3 P42263 1/20 0.90
SLC1A3 P43003 1/20 0.90
SLC1A2 P43004 1/20 0.90
SLC1A1 P43005 1/20 0.90
GRIA4 P48058 1/20 0.90
GRIN1 Q05586 1/20 0.90
GRIN2A Q12879 1/20 0.90
GRIK2 Q13002 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL563909 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL4261783 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL4261779 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL21930645 0.98 GRM8 (0.86) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL9534869 0.98 GRM8 (0.86) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL8649393 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL8648787 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL17127348 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330484 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL248800 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001891-A1 FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF KEYMED BIOSCIENCES (CHENGDU) CO., LTD. (CN) 2026-01-01 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4623936-A1 FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF Keymed Biosciences (Chengdu) Co., Ltd. (CN) 2025-10-01 EP claimed
EP-4600271-A2 BIOACTIVE MOLECULE CONJUGATE, PREPARATION METHOD AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-13 EP claimed
EP-4594492-A1 MODIFIED DOUBLE-STRANDED RNA AGENTS Alnylam Pharmaceuticals, Inc. (US) 2025-08-06 EP claimed
WO-2025040012-A1 PENTACYCLIC ACTIVE COMPOUND AND CONJUGATE THEREOF AND USE THEREOF 康诺亚生物医药科技(成都)有限公司 2025-02-27 WO claimed
WO-2025035608-A1 GLUTAMIC ACID UREA COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF, NUCLIDE TARGETING PROBE AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION 厦门大学 2025-02-20 WO claimed
WO-2024239281-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
US-20240368583-A1 DNA CONSTRUCTS, RECOMBINANT CELLS COMPRISING THEREOF, BACTERIAL PROBES, METHODS FOR THEIR PREPARATION, AND METHOD OF USING THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-11-07 US claimed
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
WO-2019149116-A1 METHOD FOR PREPARING CONJUGATE 四川科伦博泰生物医药股份有限公司 2019-08-08 WO claimed
EP-3411074-A2 SPECIFIC CONJUGATION LINKERS, SPECIFIC IMMUNOCONJUGATES THEREOF, METHODS OF MAKING AND USES SUCH CONJUGATES THEREOF Suzhou M-conj Biotech Co., Ltd. (CN) 2018-12-12 EP claimed
WO-2018185526-A1 CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE HANGZHOU DAC BIOTECH CO., LTD (CN) 2018-10-11 WO claimed
CN-108042811-A For treating the conjugate of the disease as caused by PSMA expression cells 恩多塞特公司 2018-05-18 CN claimed
CN-105230210-B A kind of wheat fertilizing method 太仓市永发农场专业合作社 2018-01-30 CN claimed
CN-105027788-B A kind of fertilization of rice method 太仓市永发农场专业合作社 2017-10-10 CN claimed
CN-105693379-A Seaweed polyglutamic acid urea and production method thereof 领先生物农业股份有限公司 2016-06-22 CN claimed
CN-105230210-A Wheat fertilizing method TAICANG YONGFA FARM SPECIALIZED COOPERATIVE 2016-01-13 CN claimed
CN-105027788-A rice fertilizing method TAICANG YONGFA FARM SPECIALIZED COOPERATIVES 2015-11-11 CN claimed
US-20130317196-A1 TRIAZANONANE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR ENHANCED FLUORINE-18 LABELING SNU R&DB FOUNDATION (KR) 2013-11-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130317196-A1 TRIAZANONANE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR ENHANCED FLUORINE-18 LABELING SLC10A1, SLCO1B1, SLCO1B3 GRM8 1159/4885GRM6 3023/4885GRM7 2490/4885
US-20260001891-A1 FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF HCCS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1 GRM8 2571/4885GRM6 1935/4885GRM7 2006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.