Glutamic Acid

Glutamic Acid

SCHEMBL9534869

NC(N)=O.N[C@@H](CCC(=O)O)C(=O)O.[NaH]

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.86
GRM6 O15303 2/20 0.86
GRM7 Q14831 2/20 0.86
GRM4 Q14833 2/20 0.86
GSR P00390 2/20 0.86
GRIN2D O15399 1/20 0.86
GRIN3B O60391 1/20 0.86
CYP1A2 P05177 1/20 0.86
GRIK1 P39086 1/20 0.86
GRM5 P41594 1/20 0.86
GRIA1 P42261 1/20 0.86
GRIA2 P42262 1/20 0.86
GRIA3 P42263 1/20 0.86
SLC1A3 P43003 1/20 0.86
SLC1A2 P43004 1/20 0.86
SLC1A1 P43005 1/20 0.86
GRIA4 P48058 1/20 0.86
GRIN1 Q05586 1/20 0.86
GRIN2A Q12879 1/20 0.86
GRIK2 Q13002 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL563907 0.98 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL4261783 0.98 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL563909 0.98 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL4261779 0.98 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL21930645 0.95 GRM8 (0.86) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL25423978 0.95 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL333301 0.95 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1269250 0.95 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL4605044 0.95 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL26086436 0.95 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5270025-A Methods for controlling N2 O emissions and for the reduction of NO.sub.x emissions in combustion systems while controlling N2 O emissions ENERGY & ENVIRONMENTAL RESEARCH CORP. (US) 1993-12-14 US disclosed
WO-1993019006-A1 METHOD FOR CONTROLLING N2O EMISSIONS AND FOR THE REDUCTION OF NOx AND SOx EMISSIONS IN COMBUSTION SYSTEMS ENERGY & ENVIRONMENTAL RESEARCH CORP. (US) 1993-09-30 WO disclosed