Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312147 | 0.89 | KMT2A (0.76) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11445596 | 0.87 | KMT2A (0.73) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11105348 | 0.85 | KMT2A (0.57) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11106188 | 0.85 | KMT2A (0.57) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL3127812 | 0.84 | BCL9 (0.60) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL11468430 | 0.83 | CACNA1B (0.51) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL29279079 | 0.83 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL15763920 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL9171166 | 0.83 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL6282777 | 0.83 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955823-B | Carboxy-substituted imidazo [1,2-a ] pyridinecarboxamides and their use as stimulators of soluble guanylate cyclase | 拜耳制药股份公司 | 2017-04-19 | — | — | CN | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| CN-120157577-A | Application of tetra-n-butyl ammonium bromide as catalyst in catalyzing reaction of methoxyl aromatic hydrocarbon and acyl bromide | 皖南医学院 | 2025-06-17 | — | — | CN | disclosed |
| CN-119012965-B | Mass spectrometry method and system | 巴塞尔儿童医院 | 2025-06-10 | — | — | CN | disclosed |
| CN-119661547-A | Tricyclic pyridine compounds as SARM1 enzyme activity inhibitors and application thereof | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119012965-A | Mass spectrometry method and system | 巴塞尔儿童医院 | 2024-11-22 | — | — | CN | disclosed |
| EP-4455159-A1 | GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER | 3B Pharmaceuticals GmbH (DE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118666764-A | Triazole amide compound, preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-09-20 | — | — | CN | disclosed |
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5620989-A | NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS; PARTICULARLY ANTAGONISTIC FOR SUBSTANCE P | MERCK SHARP & DOHME LIMITED (GB) | 1997-04-15 | — | — | US | disclosed |
| EP-0715627-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | Pfizer Limited (GB) | 1996-06-12 | — | — | EP | disclosed |
| EP-0666856-A1 | 4-ARYLMETHYLOXYMETHYL PIPERIDINES AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010165-A1 | 4-ARYLMETHYLOXYMETHYL PIPERIDINES AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |
| CN-1083473-A | New imidazolium compounds and pharmaceutical composition thereof | SMITHKLINE BEECHAM CORP (US) | 1994-03-09 | — | — | CN | disclosed |
| CN-87100040-A | The alkylamine that alkyl diaryl replaces, its preparation technology's method, the medicine of using and containing this compounds | — | 1987-09-16 | — | — | CN | disclosed |
| US-4411975-A | TONER AND DEVELOPER FOR ELECTROSTATIC IMAGES | XEROX CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |