Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.88 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | PRKACA | P17612 | 1/20 | 0.64 |
| ▸ | FLT1 | P17948 | 1/20 | 0.64 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | AKT1 | P31749 | 1/20 | 0.64 |
| ▸ | FLT4 | P35916 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | FLT3 | P36888 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640277 | 0.93 | SMN1; SMN2 (1.00) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL1101522 | 0.88 | ALDH1A1 (0.77) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL5968858 | 0.88 | ALDH1A1 (0.77) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL751213 | 0.88 | ALDH1A1 (0.77) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL17369057 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL3755011 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL2919150 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL3756762 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL13947536 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNASMN1; SMN2NPC1POLB | |
| SCHEMBL2407415 | 0.83 | SMN1; SMN2 (0.77) | ALDH1A1LMNASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |