Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 5/20 | 0.70 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MLYCD | O95822 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | AGER | Q15109 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645455 | 0.93 | NSD2 (0.67) | LIMK2NSD2KMT2AMEN1MLYCD | |
| SCHEMBL1003665 | 0.88 | KMT2A (0.83) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL2921609 | 0.85 | KMT2A (0.68) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL3455399 | 0.85 | LIMK2 (0.69) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL30131237 | 0.84 | NSD2 (0.68) | LIMK2NSD2KMT2AMLYCDHDAC1 | |
| SCHEMBL5646698 | 0.84 | NSD2 (0.68) | LIMK2NSD2KMT2AMEN1MLYCD | |
| SCHEMBL19630546 | 0.83 | KMT2A (0.66) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL4937857 | 0.83 | HDAC1 (0.66) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL5645193 | 0.83 | MEN1 (0.78) | LIMK2KMT2AMEN1MLYCDHDAC1 | |
| SCHEMBL14812071 | 0.82 | HDAC1 (0.64) | LIMK2KMT2AMEN1MLYCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |