Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.52 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686616 | 0.83 | HPGD (0.64) | AKR1B1KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL5645795 | 0.83 | KCNA5 (0.55) | AKR1B1KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL28695543 | 0.82 | HPGD (0.52) | AKR1B1KCNA5HPGDPOLBHTT | |
| SCHEMBL3460904 | 0.80 | EPHX2 (0.57) | AKR1B1KCNA5HPGDPOLBMAOB | |
| SCHEMBL28710986 | 0.79 | KMT2A (0.62) | HPGDPOLBHTTTSHRKMT2A | |
| SCHEMBL2204592 | 0.78 | KCNA5 (0.67) | AKR1B1KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL21196354 | 0.76 | HPGD (0.49) | AKR1B1KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL10107711 | 0.76 | HPGD (0.56) | HPGDPOLBHTTTSHRKMT2A | |
| SCHEMBL10487969 | 0.76 | AKR1B1 (0.64) | AKR1B1KCNA5HPGDKMT2AALDH1A1 | |
| SCHEMBL6782132 | 0.75 | EPHX2 (0.56) | MAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |